Aldolase

Aldolase is an enzyme belonging to the lyase group, involved in the energy metabolism of carbohydrates. Aldolase is found in skeletal muscle, liver, kidney, red blood cells and cardiac muscle. Aldolase determination is mainly used for diagnosing and monitoring the treatment of patients with muscular dystrophy Muscular dystrophy - a group of genetically determined muscle diseases, caused by mutations in genes encoding proteins that make up the the muscle cell membrane, cytoskeleton and membrane of the nucleus of the muscle cell muscle cell. In the course of the disease there is a progressive weakening and muscle atrophy.