Fluoxetine (Prozac) in urine

Fluoxetine is a drug belonging to the selective inhibitors of serotonin reuptake. Its action is to block the transport of serotonin back into the nerve cell. This causes an increase in serotonin in the central nervous system. Fluoxetine is antidepressant drug used in adults and also in obsessive-compulsive disorder, bulimia, and depression. Determination of concentration is helpful in monitoring therapy and in suspected intoxication with the drug. Detectable plasma concentrations are found even several weeks after drug withdrawal.