Ascaris lumbricoides P1

Clinical significance:

Allergic diseases are among one of the most common conditions of modern civilization. It is estimated that between 10-30% of the population suffers from allergies, depending on the form of the condition. Most of the allergic diseases are chronic and patients must be treated systematically, sometimes for life (such is the case with bronchial asthma).

Allergy, or hypersensitivity, is the term used to describe an excessively heightened, tissue-damaging response of the immune system upon contact with a foreign antigen (allergen). Allergens bind to specific antibodies from the immunoglobulin E group. They can sensitize the body by inhalation, ingestion, through the skinhand or parenterally.

The immunological diagnosis of allergy uses determinations of total IgE (cIgE) and specific IgE (sIgE) concentrations, i.e. antibodies against specific allergens (sensitizing substances).
They are an alternative to skinr tests (they exclude false-negative results in peopler with extensive skinr tests or in patientsr with skinry hyperreactivity).

The tests are safe and can be performed in any person of any age, including children or elderly people and even in patientswho require continuous administration of anti-allergic and anti-inflammatory drugs (these drugs do not affect the results of sIg determinations).