Metanephrine
Clinical significance
Metanephrine (methoxyadrenaline) - a metabolite of epinephrine. Catecholamines, mainly adrenaline and norepinephrine, are formed in the pheochromocytes of the adrenal medulla from tyrosine. The secretion of catecholamines is the body's response to stressful stimuli such exercise, ból, hypoxia, hypoglycemia. The release of catecholamines causes an increase in blood pressure, acceleration of heart rate, elevation of glucose levels and ogól mobilization of the body. Determination of catecholamine metabolites is performed in the diagnosis of chromaffin tumors and other neuroendocrine tumors thatóre able to produce catecholamines, resulting in an increase in catecholamines and their metabolitesóin the blood and urine. Metanephrines are also determined in patientsów with hypertension.
Patient Preparation
Material: EDTA plasma
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