Onconeuronal antibodies are antibodies that attack and
destroy the nervous system. Determinations of onconeuronal antibodies
allow, with an appropriate clinical picture, to make a
confident diagnosis of neurological paraneoplastic syndrome and
taking diagnostic measures aimed at determining the
localization of the primary tumor and implementation of specific
treatment. Each of the antibodies is specific to a particular
paraneoplastic syndrome and cancer. Anti - CV2 antibodies are
characteristic of: cerebellar ataxia, sensory-motor neuropathy, choroiditis, retinitis pigmentosa, and
motor, choroiditis, retinopathy, encephalomyelitis,
small cell lung cancer, thymoma.