Onconeuronal antibodies are antibodies that attack and
destroy the nervous system. Determinations of onconeuronal antibodies
allow, with an appropriate clinical picture, to make a
confident diagnosis of neurological paraneoplastic syndrome and
taking diagnostic measures aimed at determining the
localization of the primary tumor and implementation of specific
treatment. Each of the antibodies is specific to a particular
paraneoplastic syndrome and cancer. Anti-Hu antibodies are
characteristic of such neurological syndromes as encephalomyelitis
encephalomyelitis, limbic encephalitis, cerebellar degeneration and
sensory neuropathy. They can accompany small cell carcinoma
lung.