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Tyroxine-binding globulin TBG - is the main protein
transporting thyroxine in the blood. An increase in TBG levels (e.g., during
pregnancy, during the use of oral contraceptives or
hormone treatment) in people with a normally functioning thyroid gland
can cause an increase in the concentration of total thyroxine (T4) -
with normal values of TSH and free thyroid hormones.