EMA test, assesment of red blood cell membrane disorders

EMA test - evaluation of erythrocyte membrane disorders

Clinical significance

The EMA test is used in the diagnosis of congenital spherocytosis. Congenital spherocytosis (HS) is one of the most common congenital hemolytic anemias. It is caused by abnormalities in the structure or amount of membrane proteins or cytoskeleton of red blood cells. The EMA test is a highly sensitive and specific screening test thatós able to quickly assess the possibility of congenital spherocytosis. The advantage of this test is the small amount of material needed for the test and the fact that it can be performed 3-7 days after blood collection. This is very important in newbornsów and infants whoóre in need of immediate blood transfusion, and in whom the cause of anemia is unknown.

Patient Preparation

Material: EDTA blood