Antigen detection of Rota- and Adenoviruses

Rotavirusw antigen detection and Adenovirusw testing

Both rotaviruses and adenoviruses are subgroups of pathogensthatare among the most common etiological agents responsible for causing acute gastrointestinal infections in infants and children. The condition is also known as gastroenteritis, or gastrointestinal flu.

Rotaviruses are a genus of virusesw that contain genetic material in the form of a double-stranded RNA strand. There are 7 majors subtypesof this virus, designated sequentially by the letters A through G, with only rotaviruses A, B and C being infectious to humans. Rotavirus A is usually responsible for the infections (in more than 90% of casesin), and it is this pathogen that is the most common cause of acute infectious diarrhea in children. The pathological symptoms are due to the destructive effect of rotavirus on the epithelial cells of the small intestine in the course of an active infection.

Adenoviruses have a different genetic material, as it occurs in the form of a doubley DNA strand. Among them, too, there is a division into several subtypesof whichmore than 60 separate entities have been described to date. Depending on the type in question, they can cause a rve variety of diseases, such as respiratory infections, conjunctivitis and cystitis as well as inflammation in the gastrointestinal tract.

The subtype can cause a wide range of diseases, such as respiratory infections, conjunctivitis and inflammation in the gastrointestinal tract

Because of the multiplicity of possible conditions, as well as the significant rs of symptoms, accurate identification of the etiologic agent is of utmost importance in planning appropriate therapeutic management.

Detection of antigensw Rotavirusw and Adenovirusw – when to perform?

This test involves the detection of specific proteins thattestify to the presence of a virus of a particular type in the material being tested, which is a diarrheal stool specimen. These organic compounds are just called antigens, and a positive result of this test (that is, confirming their presence) indicates an active infectious process ongoing in the patient's body.

This test allows faster diagnosis in the course of acute diarrhea, as it is able to immediately detect the two main etiological agents, namely rotaviruses and adenoviruses, which significantly reduces the time required to make an accurate diagnosis.

Infection with these pathogens most often occurs through the oral route, that is, by ingesting food containing virus particles. In addition, somere of these viruses can also be transmitted via the droplet route, that is, through mwienie, coughing and sneezing, or contact with an infected surface.

The most important part of prevention, or prevention of infection, is proper hygiene and cleanliness of the child's environment. Particular attention should be paid to objects with which the child often comes into contact, such as toys.

Detection of antigensw Rotavirusw and Adenovirusw – who should perform?

The picture of gastroenteritis caused by both rotaviruses and adenoviruses is quite similar. The disease primarily affects young children, especially those in large concentrations, such as nurseries and kindergartens, and occurs most often in the autumn-winter season.

In adults, it rarely appears

Gastroenteritis caused by these pathogens rarely occurs in adults - this is probably due to their acquiring immunity to these pathogens earlier in life.

Disease symptomsre rotaviruses and adenoviruses may be responsible for include:

• watery diarrhea
• mucus in the stool
• vomiting
• ble abdomen
• fever

Additionally, symptoms from other systems may become apparent, such as symptoms of gral infection, which can pose some difficulty in the diagnostic process. Intestinal inflammation usually has an acute course, but resolves on its own within a week or so.

The greatest danger, especially for pediatric patientslly, is the severe dehydration that occurs during its course, which can result in the need for hospital treatment due to the difficulty of replenishing fluidslly at home. With each infection the body acquires more and more immunity, so the most severe course usually has the first episode of infection-each subsequent episode will be milder.