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- Anti-endomysium antibodies - IgA (IIF)
Anti-endomysium antibodies - IgA (IIF)
Test the level of IgA antibodies against smooth muscle endomysium (EmA) in the blood.
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Test the level of IgA antibodies against smooth muscle endomysium (EmA) in the blood. The EmA test is used in the diagnosis of celiac disease and food intolerance.
The test is used in the diagnosis of celiac disease and food intolerance
Celiac disease, or visceral disease, is a lifelong immune-mediated genetic disorder characterized by gluten intolerance. The toxic effect of gluten leads to atrophy of the villi of the small intestine, which increase its surface area and are responsible for absorption of nutrients.
The toxic effect of gluten leads to impaired absorption of food,which leads to a variety of clinical symptoms. The concentration of IgA antibodies against smooth muscle endomysium (EmA) in the blood is dependent on gluten exposure. The level of IgA antibodies against EmA decreases with a gluten-free diet.
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The test involves the determination of antibodies against reticulin and against smooth muscle endomysium in the IgA and IgG classes, which are the primary serological markers of celiac disease (visceral disease).
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